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Reductive deoxygenation of indan-1-ols by ZnI2NaCNBH3

✍ Scribed by Elba N. Alesso; Daniel E. Bianchi; Liliana M. Finkielsztein; Beatriz Lantaño; Graciela Y. Moltrasio; Jose M. Aguirre


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
150 KB
Volume
36
Category
Article
ISSN
0040-4039

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✍ Michael H. Kress; Chunhua Yang; Nobuyoshi Yasuda; E.J.J. Grabowski 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 264 KB

An efficient, diastereoselective [2,3]-Wittig rearrangement of~x-allyloxyamide enolates has been developed using (1S,2R)-l-amino-indan-2-ol as a chiral auxiliary. After auxiliary removal, the resultant optically active a-hydroxy acids have been transformed to functionalized amino acid derivatives.