Computer simulation studies of the fidelity of DNA polymerases
✍ Scribed by Jan Florián; Myron F. Goodman; Arieh Warshel
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2003
- Tongue
- English
- Weight
- 815 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0006-3525
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
To obtain new insight into the nature of the correlations in distributions of nucleotides in DNA sequences, an efficient algorithm is presented by means of which one can generate nucleotide sequences with prescribed correlational properties. It is demonstrated in the case of human T-cell receptor be
The Monte Carlo technique is used to study the effect of an external field on a lattice of particles interacthtg via a Pz(cos pii> potential\_ The director can be pinned by the field although the orientational order is increased slightly. The observed field dependence of the long-and short-range ord
These studies have been conducted as a first step toward investigating the molecular mechanism by which DNA-dependent RNA polymerase recognizes a specific region of DNA. The DNA moieties are either bound to or freed from RNA polymerase. Results obtained so far indicate that the DNA moieties remainin
## Abstract DNA polymerase epsilon is a mammalian polymerase that has a tightly associated 3′→5′ exonuclease activity. Because of this readily detectable exonuclease activity, the enzyme has been regarded as a form of DNA polymerase delta, an enzyme which, together with DNA polymerase alpha, is in