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Studies on binding of RNA polymerase to DNA

✍ Scribed by T. Kameyama; A. Matsukage; Y. Tanaka

Publisher: John Wiley and Sons
Year: 1969
Tongue: English
Weight: 300 KB
Volume: 74
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040740422

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✦ Synopsis

These studies have been conducted as a first step toward investigating the molecular mechanism by which DNA-dependent RNA polymerase recognizes a specific region of DNA. The DNA moieties are either bound to or freed from RNA polymerase. Results obtained so far indicate that the DNA moieties remaining as resistant segments after deoxyribonuclease digestion should be regarded as the binding regions on DNA. The results described here were carried out by use of E. coZi and lambda DNA.

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