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Computational Study of Pharmacophores: β-Lactams

✍ Scribed by Novak, Igor; Chua, Pei Juan


Book ID
125911434
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
56 KB
Volume
110
Category
Article
ISSN
1089-5639

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Electrochemical studies on β-lactams. Pa
✍ Maria Antonietta Casadei; Achille Inesi; Franco Micheletti Moracci; Donatella Oc 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 547 KB

Electroreduction of 3-bromo-and 3,3-dichloro-JMzctams 1 carried out at the potential of the first voltammetricpeak andin thepresence of acetic anhydridegives3-acetyl-#-lactams2. The electrosynthesis is highly stereoselective, as only the acetyl derivative with trans co@iguration is formed.