Electrochemical studies on β-lactams. Part 4. Electroacetylation of β-lactams.

✍ Scribed by Maria Antonietta Casadei; Achille Inesi; Franco Micheletti Moracci; Donatella Occhialini

• Publisher: Elsevier Science
• Year: 1989
• Tongue: French
• Weight: 547 KB
• Volume: 45
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(01)89156-0

✦ Synopsis

Electroreduction of 3-bromo-and 3,3-dichloro-JMzctams 1 carried out at the potential of the first voltammetricpeak andin thepresence of acetic anhydridegives3-acetyl-#-lactams2. The electrosynthesis is highly stereoselective, as only the acetyl derivative with trans co@iguration is formed.