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Computation of pharmacophore models for the prediction of mitogen-activated protein kinase activated protein kinase-2 inhibitory activity of pyrrolopyridines

✍ Scribed by Upasna Kaushik, Vikas Sharma, Vipin Kumar

Book ID
118778052
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
416 KB
Volume
21
Category
Article
ISSN
1054-2523

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## Abstract Intermediate filament (IF) networks can be regulated by phosphorylation of unit proteins, such as vimentin, by specific kinases leading to reorganization of the IF filamentous structure. Recently, we identified mitogen‐activated protein kinase‐activated protein kinase‐2 (MAPKAP kinase‐2