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Complex karyotype with a masked Philadelphia translocation and variant BCR-ABL fusion in CML

โœ Scribed by Sonal R. Bakshi; Beena P. Patel; Manisha M. Brahmbhatt; Pina J. Trivedi; Sarju B. Gajjar; Ramesh R. Iyer; Esha H. Parikh; Shilin N. Shukla; Pankaj M. Shah


Book ID
113513469
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
188 KB
Volume
189
Category
Article
ISSN
0165-4608

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BCR/ABL fusion located on chromosome 9 i
โœ Anwar N. Mohamed; F. Koppitch; M. Varterasian; C. Karanes; Kai-Ling Yao; F. H. S ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 394 KB

A reciprocal translocation, t( I022)(q2Z;q I I), resulting in a masked Ph chromosome was identified in a patient diagnosed with chronic myeloid leukemia (CML). Both homologs of chromosome 9 were of the normal pattern. Two signals for the ABL probe, both of them hybridized to chromosome 9, were demon

Molecular confirmation of BCR-ABL fusion
โœ Sugandhi A. Tharapel; Cindy L. Vnencak-Jones; James A. Whitlock; Rajiv Jain ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 274 KB

W e performed molecular studies to resolve the status of BCR and ABL in the bone marrow cells of a CML patient with a Ph chromosome resulting from a complex translocation involving chromosomes 9, 15, and 22. D N A digestion with BomHI, Hindlll, and Bglll, followed by hybridization to a bcr-specific