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Complete cytogenetic and molecular response after imatinib treatment for chronic myeloid leukemia in a patient with atypical karyotype and BCR-ABL b2a3 transcript

✍ Scribed by Barbara Pienkowska-Grela; Renata Woroniecka; Iwona Solarska; Kinga Kos; Anna Pastwińska; Lech Konopka; Miroslaw Majewski


Book ID
113513088
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
198 KB
Volume
174
Category
Article
ISSN
0165-4608

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Since very few unusual BCR/ABL fusion transcripts in chronic myeloid leukemia have been reported, no clear evidence exists concerning their clinical and prognostic implications. We describe here a CML case with normal karyotype at standard cytogenetics and an atypical e6a2 BCR/ABL fusion transcript,