Complementary Asymmetric Routes to ( R )-2-(7-Hydroxy-2,3-dihydro-1 H -pyrrolo[1,2- a ]indol-1-yl)acetate
✍ Scribed by Schrader, Thomas O.; Johnson, Benjamin R.; Lopez, Luis; Kasem, Michelle; Gharbaoui, Tawfik; Sengupta, Dipanjan; Buzard, Daniel; Basmadjian, Christine; Jones, Robert M.
- Book ID
- 118164579
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 320 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1523-7060
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Mitomycin antibiotics (I) have a novel ring system that is aziridinopyrrolo II 1,2-a indoloquinone(1). In synthetic studies on mitomycin analogs Lederle group synthesised 7-benzyloxy-9H-pyrrolo 1,2-a indole(2) and substituted 2,3r.
The two pyrrolidine rings in the title compound, C~25~H~22~N~2~O~6~, adopt envelope conformations. Molecules are stabilized by intramolecular O—H...O hydrogen bonds, and linked into centrosymmetric dimers by intermolecular N—H...O hydrogen bonds.