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Competitive NMDA receptor antagonists enhance the antielectroshock activity of various antiepileptics

✍ Scribed by Teresa Pietrasiewicz; Grażyna Czechowska; Marek Dziki; Waldemar A. Turski; Zdzisław Kleinrok; Stanisław J. Czuczwar


Book ID
115888720
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
635 KB
Volume
250
Category
Article
ISSN
0014-2999

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The N-methyl-D-aspartate (NMDA)-subtype of glutamate receptors has been well described as a result of the early appearance of NMDA antagonists, but no potent antagonist for the "non-NMDA" glutamate receptors has been available. Quinoxaline- diones have now been found to be potent and competitive ant