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Comparison of von Willebrand factor antigen, von Willebrand factor-cleaving protease and protein S in blood components used for treatment of thrombotic thrombocytopenic purpura

✍ Scribed by H. Yarranton; A. S. Lawrie; G. Purdy; I. J. Mackie; S. J. Machin


Book ID
110756822
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
169 KB
Volume
14
Category
Article
ISSN
0958-7578

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## Abstract Decreased von Willebrand factor (VWF)‐cleaving protease activity (<5%) has been implicated in patients with congenital thrombotic thrombocytopenic purpura–hemolytic uremic syndrome (Upshaw‐Schulman syndrome) and associated with mutations within the __ADAMTS13__ gene. In this report, we