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The active conformation of von Willebrand factor in patients with thrombotic thrombocytopenic purpura in remission

✍ Scribed by E. GROOT; R. FIJNHEER; S. A. E. SEBASTIAN; PH. G. DE GROOT; P. J. LENTING


Book ID
109152920
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
270 KB
Volume
7
Category
Article
ISSN
1538-7933

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## Abstract Decreased von Willebrand factor (VWF)‐cleaving protease activity (<5%) has been implicated in patients with congenital thrombotic thrombocytopenic purpura–hemolytic uremic syndrome (Upshaw‐Schulman syndrome) and associated with mutations within the __ADAMTS13__ gene. In this report, we