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Comparison of the labelling characteristics of mercaptoacetyltriglycine (MAG3) with different S-protective groups

โœ Scribed by Subhani M. Okarvi; Paul Adriaens; A. Verbruggen


Publisher
John Wiley and Sons
Year
1997
Tongue
French
Weight
1023 KB
Volume
39
Category
Article
ISSN
0022-2135

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๐Ÿ“œ SIMILAR VOLUMES


Synthesis and biological characteristics
โœ S. M. Okarvi; P. Adriaens; A. M. Verbruggen ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 154 KB

A number of MAG 3 -derivatives, containing the three-amide functions modified by inverting the sequence -CO-NH-to -NH-CO-in the firstand/or second-amide functions, have been labelled with 99m Tc in order to study the renal characteristics of the resulting MAG 3 -derivatives versus the reference 99m

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## Abstract Eight novel derivatives of MAG~3~, containing in their structure two instead of three amide functions, have been synthesized and evaluated. The synthesized ligands were labelled with ^99m^Tc by exchange labelling at 100ยฐC and/or by a direct labelling method at room temperature. After la