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Comparison of the anti-dopamine D2 and anti-serotonin 5-HT2A activities of chlorpromazine, bromperidol, haloperidol and second-generation antipsychotics parent compounds and metabolites thereof

โœ Scribed by Suzuki, H.; Gen, K.; Inoue, Y.

Book ID
125525885
Publisher
SAGE Publications
Year
2013
Tongue
English
Weight
525 KB
Volume
27
Category
Article
ISSN
0269-8811

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โœ Hidenobu Suzuki; Keishi Gen ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 176 KB

Objective Blonanserin (BNS) possesses anti-serotonin 5-HT 2A activity in addition to anti-dopamine D 2 activity, which is characteristic of second-generation antipsychotics, little information is available on its pharmacologic profile in vivo. We investigated the BNS daily dose, plasma concentration