The relationship between the plasma concentration of blonanserin, and its plasma anti-serotonin 5-HT2A activity/anti-dopamine D2 activity ratio and drug-induced extrapyramidal symptoms

The relationship between the daily dose,

The relationship between the daily dose, the plasma concentration of blonanserin, and its plasma anti-dopamine D2 and anti-serotonin 5-HT2A activity

✍ Hidenobu Suzuki; Keishi Gen 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 176 KB

Objective Blonanserin (BNS) possesses anti-serotonin 5-HT 2A activity in addition to anti-dopamine D 2 activity, which is characteristic of second-generation antipsychotics, little information is available on its pharmacologic profile in vivo. We investigated the BNS daily dose, plasma concentration