## Abstract Multiβcomponent mixtures of controlled drugs, drug impurities, and adulterants have been analyzed by capillary SFCβFID, packed column SFCβUV, and capillary SFCβMS. Isocratic packed column SFC has been performed with binary and ternary mobile phases using a single syringe pump. The combi
Comparison of packed and capillary columns for practical SFC separations
β Scribed by H. E. Schwartz; P. J. Barthel; S. E. Moring; T. L. Yates; H. H. Lauer
- Book ID
- 112356307
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 276 KB
- Volume
- 330
- Category
- Article
- ISSN
- 1618-2650
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## Abstract Preparation of packed capillary columns with supercritical carbon dioxide as the packing carrier is demonstrated; column performance was evaluated by both HPLC and SFC. It is shown that this procedure yields excellent column performance. The density of the packed bed can be controlled b
## Abstract Residual adsorptive activity of reversed phase (RP) column packings used in supercritical fluid chromatography (SFC) can be significantly reduced by a dynamic __inβsitu__ silanization with diphenyltetramethyldisilazane (DPTMDS). RPβmaterials thus deactivated were characterized both chro