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Comparison of High Performance Capillary Electrophoresis and Liquid Chromatography for the Determination of Acyclovir and Guanine in Pharmaceuticals and Urine

✍ Scribed by S. S. Zhang; H. X. Liu; Y. Chen; Z. B. Yuan

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
195 KB
Volume
10
Category
Article
ISSN
0269-3879

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✦ Synopsis

High-performance capillary electrophoresis (HPCE) and high-performance liquid chromatography (HPLC) were developed and applied to the determination of acyclovir (ACV) and guanine (C) in pharmaceuticals. The comparison study showed that two methods gave comparable results in linear range, recovery and reproducibility. HPCE was used for the determination of ACV and G in urine; the recovery was better than 813% and the RSD was less than 4.4%.

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