𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparison of growth kinetics of producing and nonproducing hybridoma cells in batch culture

✍ Scribed by Kelly K. Frame; Wei-Shou Hu

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
679 KB
Volume
13
Category
Article
ISSN
0141-0229

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Kinetic study of hybridoma cell growth i
Kinetic study of hybridoma cell growth in continuous culture: II. Behavior of producers and comparison to nonproducers
✍ Kelly K. Frame; Wei-Shou Hu πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 756 KB

A hybridoma cell line, AFP-27-P, was cultivated in continuous culture under glucose-limited conditions. The viable cell concentration, dead-cell concentration, and cell volume all varied with the dilution rate. A model previously developed for a nonproducing clone of the same cell line, AFP-27-NP, w

Kinetic study of hybridoma cell growth i
Kinetic study of hybridoma cell growth in continuous culture. I. A model for non-producing cells
✍ Kelly K. Frame; Wei-Shou Hu πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 906 KB

## Abstract The kinetic behavior of a nonproducing hybridoma clone AFP‐27‐NP was investigated in continuous culture under glucose‐limited conditions. A total of more than 21, 000 h of cultures were operated at dilution rates ranging from 0.01 to 0.06 h^βˆ’1^. The viable cell concentrations, dead cell

Dichloroacetate increases cell and antib
Dichloroacetate increases cell and antibody yields in batch cultures of a hybridoma cell line
✍ Kevin Murray; Keith Gull; Alan J. Dickson πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 561 KB

We have studied the effect of the pyruvate dehydrogenase (PDH) activator, dichloroacetate (DCA), on the growth, metabolism, and productivity of the PQXB 1/2 hybridoma cell line. In control batch cultures, cessation of growth and the onset of decline phase coincided with the time at which the media b