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Comparison of [11C]methyl triflate and [11C]methyl iodide in the synthesis of PET radioligands such as [11C]β-CIT and [11C]β-CFT

✍ Scribed by Kjell Någren; Christer Halldin; Lars Müller; Carl-Gunnar Swahn; Pertti Lehikoinen


Book ID
116172073
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
309 KB
Volume
22
Category
Article
ISSN
0969-8051

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The monoamine transporter was studied in 4 healthy controls and 5 patients with early Parkinson's disease (PD), who had not received any antiparkinsonian medication, by means of positron emission tomography (PET) using two novel ligands, ["CIP-CIT and ["CIP-CFT. Both ligands showed highest uptake in