Comparative use of benzhydrylamine and chloromethylated resins in solid-phase synthesis of carboxamide terminal peptides. Synthesis of oxytocin derivatives
โ Scribed by Hruby, Victor J.; Upson, Donald A.; Agarwal, Nirankar S.
- Book ID
- 126077079
- Publisher
- American Chemical Society
- Year
- 1977
- Tongue
- English
- Weight
- 814 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
The terminating agent was used to block any N-terminal amino groups which had not reacted in the coupling steps. Blake and Li2 also employed this procedure to assure complete acylation of the N-terminal amino group in the solid-phase synthesis of a heptapeptide. They reported that the acetylation p
## Abstract Wellโcharacterized resins of high purity are critical for effective solid phase peptide synthesis (SPPS). The quality of commercial (4โmethyl)benzhydrylamineโresin (MBHAโresin), used for the synthesis of peptide amides, is not consistent and residual ketone functionalities are frequentl