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Comparative study on cytogenetic damage induced by homo-aza-steroidal esters in human lymphocytes

โœ Scribed by D. Mourelatos; A. Papageorgiou; L. Boutis; P. Catsoulacos


Book ID
113253047
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
271 KB
Volume
334
Category
Article
ISSN
0165-1161

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The cytogenetic effects of homo-aza-steroidal ester (ASE) on Chinese hamster ovary (CHO) cells in vitro are reported. It was found that treatment of cells with a dose as low as 0.025 pglml of ASE causes a significant number of abnormal metaphases containing mostly chromatid-type aberrations. Similar