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Comparative study of intranasal midazolam and intravenous diazepam sedation for procedures and seizures

✍ Scribed by Pankaj Mittal; Ram Manohar; A. K. Rawat

Book ID
110666890
Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
282 KB
Volume
73
Category
Article
ISSN
0019-5456

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Pharmacokinetics of midazolam in childre
Pharmacokinetics of midazolam in children: comparative study of intranasal and intravenous administration
✍ E. Rey; L. Delaunay; G. Pons; I. Murat; M. O. Richard; C. Saint-Maurice; G. Oliv πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 294 KB

Twelve children 1-5 y old were randomly assigned to receive midazolam 0.2 mg.kg-1 either by the intravenous (IV) or intranasal (IN) routes. After IN administration the rapid onset of absorption was observed (tmax 12 min). After both routes of administration the half-life was similar (2.2 h IN and 2.