## Abstract The association of precore stop codon mutation (A1896), dinucleotide mutation (T1762/A1764) in the basic core promoter of hepatitis B virus (HBV) genome, and genotype of HBV with fulminant or subfulminant hepatitis remains controversial. We studied HBV genotypes as well as mutations in
Comparative study of genotype B and C hepatitis B virus-induced chronic hepatitis in relation to the basic core promoter and precore mutations
โ Scribed by KOJI WATANABE; TORU TAKAHASHI; SUMIO TAKAHASHI; SHOGO OKOSHI; TAKAFUMI ICHIDA; YUTAKA AOYAGI
- Book ID
- 108950022
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 350 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0815-9319
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## Abstract Using phylogenetic analysis and pairwise comparison of 670 complete hepatitis B virus (HBV) genomes, we demonstrated that nucleotide divergence greater than 7.5% can be used to separate strains into genotypes AโH. Strains can be separated into subgenotypes when two criteria are met: nuc
The precore-core gene of hepatitis B virus (HBV) was directly sequenced from serum samples of 42 patients with chronic B hepatitis (19 hepatitis B e antigen [HBeAg]+ and 23 anti-me+). Viral genotypes were determined by comparison with ll reference sequences and by restriction analysis. Genotype A wa