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Comparative Linkage-Disequilibrium Analysis of the β-Globin Hotspot in Primates

✍ Scribed by Jeffrey D. Wall; Linda A. Frisse; Richard R. Hudson; Anna Di Rienzo

Book ID
117854343
Publisher
American Society of Human Genetics
Year
2003
Tongue
English
Weight
896 KB
Volume
73
Category
Article
ISSN
0002-9297

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✍ Dr. Ranajit Chakraborty; D. C. Rao 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 595 KB

Simple estimators of gene frequencies and linkage disequilibria are proposed when haplotype data are available from four parental chromosomes of a child (or fetus) for whom genetic counseling is sought for a disease condition. The method is illustrated with restriction site polymorphisms associated