Three-locus haplotype interactions in the analysis of linkage disequilibrium
β Scribed by L. E. Nijenhuis; J. D'amaro
- Book ID
- 115093729
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 664 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0001-2815
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RFLPs of 36 normal and 41 mutant alleles at the phenylalanine hydroxylase locus were determined in 31 Portuguese kindreds. A total of 14 haplotypes including 10 normal and 7 mutant alleles were observed. Almost 75% of all mutant alleles were confined within only two haplotypes, namely haplotype 9 (1