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Global survey of haplotype frequencies and linkage disequilibrium at the RET locus

✍ Scribed by Chattopadhyay, Pratima; Pakstis, Andrew J; Mukherjee, Namita; Iyengar, Sudha; Odunsi, Adekunle; Okonofua, Friday; Bonne-Tamir, Batsheva; Speed, William; Kidd, Judith R; Kidd, Kenneth K


Book ID
110025447
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
232 KB
Volume
11
Category
Article
ISSN
1018-4813

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Linkage disequilibrium between phenylket
✍ Catherine Caillaud; Laura Vilarinho; Antoine Vilarinho; FranΓ§oise Rev; Monique B πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 578 KB

RFLPs of 36 normal and 41 mutant alleles at the phenylalanine hydroxylase locus were determined in 31 Portuguese kindreds. A total of 14 haplotypes including 10 normal and 7 mutant alleles were observed. Almost 75% of all mutant alleles were confined within only two haplotypes, namely haplotype 9 (1