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Comparative In Vitro Anti-Hepatitis C Virus Activities of a Selected Series of Polymerase, Protease, and Helicase Inhibitors

โœ Scribed by Vliegen, I.; Coelmont, L.; Leyssen, P.; Tabarrini, O.; Herdewijn, P.; Mittendorfer, H.; Easmon, J.; Cecchetti, V.; Bartenschlager, R.; Paeshuyse, J.


Book ID
111919771
Publisher
American Society for Microbiology
Year
2008
Tongue
English
Weight
153 KB
Volume
52
Category
Article
ISSN
0066-4804

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## Anti -hepatitis C virus (HCV) drug development has been challenged by a lack of experience with inhibitors inclusive of in vitro, animal model, and clinical study. This manuscript outlines activity and correlation across such a spectrum of models and into clinical trials with a novel selective