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Protease and helicase activities of hepatitis C virus genotype 4, 5, and 6 NS3–NS4A proteins

✍ Scribed by Marie-Josée Massariol; Songping Zhao; Martin Marquis; Diane Thibeault; Peter W. White

Book ID
116299531
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
805 KB
Volume
391
Category
Article
ISSN
0006-291X

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## Abstract Many viruses can inhibit protein synthesis in their host cells by targeting translation (“translational shutoff”). There are few reports on the effects of hepatitis C virus (HCV) infection on protein synthesis, because of the lack of a reproducible tissue culture system for HCV. In this