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Comparative Genotoxicity and Nephrotoxicity Studies of the Two Halogenated Flame Retardants Tris(1,3-Dichloro-2-propyl)phosphate and Tris(2,3-Dibromopropyl)phosphate

✍ Scribed by Sederlund, Erik J. ;Dybing, Erik ;Holme, Jern A. ;Hongslo, Jan K. ;Rivedal, Edgar ;Sanner, Tore ;Nelson, Sidney D.

Book ID
114800485
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
792 KB
Volume
56
Category
Article
ISSN
0001-6683

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Comparative studies on nephrotoxic effec
Comparative studies on nephrotoxic effects of Tris (2,3-dibromopropyl) phosphate and Bis (2,3-dibromopropyl) phosphate on rat urinary metabolites
✍ Masamichi Fukuoka; Terue Takahashi; Katsushi Naito; Koichi Takada πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 770 KB

The mechanism of Tris-BP or Bis-BP (a metabolite of Tris-BP) induced nephrotoxicity was investigated by determining urinary excretion of enzymes and selected metabolites. Rats received single oral doses of 0, 71.7, 143.4 and 286.8 mumol/kg tris (2,3-dibromopropyl) phosphate (Tris-BP) or bis (2,3-dib