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Mutagenicity and Nephrotoxicity of Two Tris (2,3-dibromopropyl)-phosphate Analogues: Bis (2,3-dibromopropyl) phosphate and 2,3-Dibromopropylphosphate

✍ Scribed by Søderlund, Erik ;Nelson, Sidney D. ;Dybing, Erik

Book ID
114800117
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
289 KB
Volume
51
Category
Article
ISSN
0001-6683

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Comparative studies on nephrotoxic effec
Comparative studies on nephrotoxic effects of Tris (2,3-dibromopropyl) phosphate and Bis (2,3-dibromopropyl) phosphate on rat urinary metabolites
✍ Masamichi Fukuoka; Terue Takahashi; Katsushi Naito; Koichi Takada 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 770 KB

The mechanism of Tris-BP or Bis-BP (a metabolite of Tris-BP) induced nephrotoxicity was investigated by determining urinary excretion of enzymes and selected metabolites. Rats received single oral doses of 0, 71.7, 143.4 and 286.8 mumol/kg tris (2,3-dibromopropyl) phosphate (Tris-BP) or bis (2,3-dib