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Comparative genotoxicity studies of the flame retardant tris(2,3-dibromopropyl)phosphate and possible metabolites

✍ Scribed by Jørn A. Holme; Erik J. Søderlund; Jan K. Hongslo; Sidney D. Nelson; Erik Dybing

Book ID
119092618
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
673 KB
Volume
124
Category
Article
ISSN
0165-1218

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Comparative studies on nephrotoxic effec
Comparative studies on nephrotoxic effects of Tris (2,3-dibromopropyl) phosphate and Bis (2,3-dibromopropyl) phosphate on rat urinary metabolites
✍ Masamichi Fukuoka; Terue Takahashi; Katsushi Naito; Koichi Takada 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 770 KB

The mechanism of Tris-BP or Bis-BP (a metabolite of Tris-BP) induced nephrotoxicity was investigated by determining urinary excretion of enzymes and selected metabolites. Rats received single oral doses of 0, 71.7, 143.4 and 286.8 mumol/kg tris (2,3-dibromopropyl) phosphate (Tris-BP) or bis (2,3-dib