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Comparative effects of lovastatin and chenodeoxycholic acid on plasma cholestanol levels and abnormal bile acid metabolism in cerebrotendinous xanthomatosis

✍ Scribed by Gerald Salen; A.K. Batta; G.S. Tint; Sarah Shefer


Book ID
116031083
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
754 KB
Volume
43
Category
Article
ISSN
1532-8600

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Evidence was recently presented that an essential part of the accumulation of cholestanol in patients with cerebrotendinous xanthomatosis is due to acceleration of a novel pathway, involving ?a-hydroxylated intermediates in bile acid biosynthesis as precursors (J. Clin. Invest. 1986; 75:448-456). Su