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Effect of chenodeoxycholic acid and simvastatin on cholesterol metabolism in a patient with cerebrotendinous xanthomatosis

✍ Scribed by B. Lindenthal; A. Nagel; C. Hahn; D. Lütjohann; J. Hahn; P. Wasserhess; K. von Bergmann


Book ID
118326228
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
100 KB
Volume
115
Category
Article
ISSN
0021-9150

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Evidence was recently presented that an essential part of the accumulation of cholestanol in patients with cerebrotendinous xanthomatosis is due to acceleration of a novel pathway, involving ?a-hydroxylated intermediates in bile acid biosynthesis as precursors (J. Clin. Invest. 1986; 75:448-456). Su