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Common genetic variation within IGFI, IGFII, IGFBP-1, and IGFBP-3 and endometrial cancer risk

✍ Scribed by Monica McGrath; I-Min Lee; Julie Buring; Immaculata De Vivo


Book ID
113962652
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
177 KB
Volume
120
Category
Article
ISSN
0090-8258

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## Abstract Conditions related to chronic hyperinsulinemia, such as obesity, noninsulin dependent diabetes mellitus and polycystic ovary syndrome, are associated with an increased risk of endometrial cancer. Elevated plasma IGF‐I and decreased levels of IGF‐binding proteins have been shown to be as