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Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study

✍ Scribed by Rulla M Tamimi, David G Cox, Peter Kraft, Michael N Pollak…


Book ID
120700308
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
204 KB
Volume
9
Category
Article
ISSN
1465-5411

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## Abstract Insulin‐like growth factor‐I (IGF‐I) and its major binding protein IGFBP‐3 have been implicated in breast carcinogenesis. We examined the associations between genetic variants and circulating levels of IGF‐I and IGFBP‐3 with proliferative benign breast disease (BBD), a marker of increas