Comment on a Simple and Improved Correction for Population Stratification
✍ Scribed by Seunggeun Lee; Patrick F. Sullivan; Fei Zou; Fred A. Wright
- Book ID
- 113422421
- Publisher
- American Society of Human Genetics
- Year
- 2008
- Tongue
- English
- Weight
- 81 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0002-9297
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Hidden population substructure can cause population stratification and lead to false‐positive findings in population‐based genome‐wide association (GWA) studies. Given a large panel of markers scanned in a GWA study, it becomes increasingly feasible to uncover the hidden population subs
## Abstract Confounding due to population stratification (PS) arises when differences in both allele and disease frequencies exist in a population of mixed racial/ethnic subpopulations. Genomic control, structured association, principal components analysis (PCA), and multidimensional scaling (MDS)