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Combining factors on protein and gene level to predict radioresponse in head and neck cancer cell lines

✍ Scribed by Lovisa Farnebo; Fredrik Jerhammar; Rebecca Ceder; Roland C. Grafström; Linda Vainikka; Lena Thunell; Reidar Grénman; Ann-Charlotte Johansson; Karin Roberg


Book ID
111255498
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
250 KB
Volume
40
Category
Article
ISSN
0904-2512

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We studied epidermal growth factor receptor (EGFR) gene amplification and expression in 11 early passage human head and neck carcinoma cell lines. Three cell lines demonstrated EGFR gene amplification and 10 lines showed an increase in EGFR mRNA when compared with normal keratinocytes, placenta, and