We studied epidermal growth factor receptor (EGFR) gene amplification and expression in 11 early passage human head and neck carcinoma cell lines. Three cell lines demonstrated EGFR gene amplification and 10 lines showed an increase in EGFR mRNA when compared with normal keratinocytes, placenta, and
✦ LIBER ✦
erbB-3, a third member of theerbB/epidermal growth factor receptor gene family: its expression in head and neck cancer cell lines
✍ Scribed by W. J. Issing; W. J. Heppt; E. R. Kastenbauer
- Book ID
- 112278518
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 657 KB
- Volume
- 250
- Category
- Article
- ISSN
- 0302-9530
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## Abstract We previously reported that expression of angiogenesis factors interleukin‐8 (IL‐8) and vascular endothelial growth factor (VEGF) is promoted by coactivation of transcription factors nuclear factor‐kappaB (NF‐κB) and activator protein‐1 (AP‐1) by interleukin‐1α in human head and neck sq