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Combined segregation and linkage analysis of HLA markers in familial psoriasis

โœ Scribed by Guo, Sun-Wei; Jenisch, Stefan; Stuart, Philip; Lange, Ethan M; Kukuruga, Debra; Nair, Rajan; Henseler, Tilo; Voorhees, John; Christophers, Enno; Elder, James T


Book ID
110025231
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
160 KB
Volume
10
Category
Article
ISSN
1018-4813

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Combined segregation and linkage analysi
โœ Leigh Pascoe; Stephanie Sherman; Danny Wu; Murray Becker; Catherine Falk ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 389 KB

Combined segregation and linkage analysis of the Genetic Analysis Workshop 5 (GAWS) data suggests a complex basis for susceptibility to insulin-dependent diabetes mellitus (IDDM). One susceptibility gene, linked to the HLA-DR region, is additive on the liability scale (d = .49 f .15,t = 2.9 f .6) wi