## Abstract We illustrate the use of Gibbs sampling for combined segregation and linkage analysis using lateβonset families in the Duke Alzheimer's disease (AD) data set. The disease penetrance model is flexible, incorporating variable age of disease onset, sporadic cases, and unknown or uncertain
β¦ LIBER β¦
Combined segregation and linkage analysis of 59 Hodgkin's disease families indicates the role of HLA determinants
β Scribed by Shugart, Yin Yao; Collins, Andrew
- Book ID
- 110024916
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 73 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1018-4813
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There is good evidence for an association between Epstein-Barr virus (EBV) and Hodgkin's disease (HD). In approximately one-third of cases, the EBV genome is detectable in Reed-Sternberg (RS) cells and there is expression of the viral nuclear antigen EBNA-1 and the latent membrane protein LMP-1. Exp