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Combined loss of BRCA1/BRCA2 in grade 3 breast carcinomas

✍ Scribed by D.P. Kelsell; N.K. Spurr; D.M. Barnes; B. Gusterson; D.T. Bishop


Book ID
118561181
Publisher
The Lancet
Year
1996
Tongue
English
Weight
313 KB
Volume
347
Category
Article
ISSN
0140-6736

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To elucidate the cellular role of BRCA2 in sporadic breast tumors, we studied the cellular localization and the expression of BRCA2 in carcinomas presenting or not allelic loss of BRCA2. The breast tumors were first classified with or without allelic loss of BRCA2 and then immunohistochemical staini