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Loss of heterozygosity in BRCA1 and BRCA2 markers and high‐grade malignancy in breast cancer

✍ Scribed by Jose M. Silva; Rocio Gonzalez; Mariano Provencio; Gema Dominguez; Jose M. Garcia; Isabel Gallego; Jose Palacios; Pilar España; Felix Bonilla


Book ID
110231924
Publisher
Springer US
Year
1999
Tongue
English
Weight
87 KB
Volume
53
Category
Article
ISSN
0167-6806

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## Abstract Previous studies have shown that breast cancers have more aggressive pathologic features in young women. In order to examine genetic alterations associated with early‐onset breast cancer, 31 patients with no known family history, aged 26–35 years at diagnosis, were examined for loss of