Loss of BRCA1 expression in sporadic male breast carcinoma
โ Scribed by Xiaoping Sun; Yun Gong; M. Sambasiva Rao; Sunil Badve
- Book ID
- 110321026
- Publisher
- Springer US
- Year
- 2002
- Tongue
- English
- Weight
- 168 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0167-6806
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๐ SIMILAR VOLUMES
To elucidate the cellular role of BRCA2 in sporadic breast tumors, we studied the cellular localization and the expression of BRCA2 in carcinomas presenting or not allelic loss of BRCA2. The breast tumors were first classified with or without allelic loss of BRCA2 and then immunohistochemical staini
The role of BRCA1 in progression of sporadic breast cancers has to date been equivocal, although preliminary studies on small numbers of samples have suggested an association between expression levels of this gene and acquisition of an invasive phenotype. We have further reasoned that loss of oestro