Combinatoric strategies for genome mapping
โ Scribed by Glen A. Evans
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 817 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Linkage analysis and association studies, two major approaches for genetic studies of human diseases, are useful for mapping genes that are highly penetrant, but both use only part of the information that is available for mapping disease genes. Therefore, they provide limited utility when used alone
Single nucleotide polymorphisms (SNPs) are the most prevalent form of DNA sequence variation in humans. At the end of 2008, public databases contained more than 12 million entries of genetic variants in humans, the vast majority of which are SNPs [1]. While the incidence of SNPs in the human genome