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Strategies for the Discovery of New Natural Products by Genome Mining

โœ Scribed by Malek Zerikly; Gregory L. Challis

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
457 KB
Volume
10
Category
Article
ISSN
1439-4227

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We have developed a strategy to apply genomics and functional genomics-based technologies to the discovery of novel proteins which represent potential therapeutic candidates. The core of this strategy is based on a process for the high-throughput discovery, full-length cDNA cloning and expression of