Combination of N-(4-hydroxyphenyl) retinamide and apigenin suppressed starvation-induced autophagy and promoted apoptosis in malignant neuroblastoma cells
โ Scribed by Nishant Mohan; Naren L. Banik; Swapan K. Ray
- Book ID
- 116773506
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 977 KB
- Volume
- 502
- Category
- Article
- ISSN
- 0304-3940
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The synthetic retinoid __N__โ(4โhydroxyphenyl)retinamide (4โHPR) has been shown to induce apoptosis in various types of tumors, including prostate cancer. We sought to examine the key mechanisms affecting the resistance to 4โHPRโinduced apoptosis in three human prostate cancer cell line
## Abstract __N__โ(4โhydroxyphenyl)retinamide (4HPR, fenretinide), a retinoic acid (RA) derivative and a potential cancer preventive agent, is known to exert its chemotherapeutic effects in cancer cells through induction of apoptosis. Earlier work from our laboratory has shown that relatively low c