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N-(4-Hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells

✍ Scribed by Kim, H-J; Chakravarti, N; Oridate, N; Choe, C; Claret, F-X; Lotan, R


Book ID
110070326
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
466 KB
Volume
25
Category
Article
ISSN
0950-9232

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Cell death induced by N-(4-hydroxyphenyl
✍ Maria Davies; Ian C. Paterson; Anu Ganapathy; Stephen S. Prime πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 French βš– 479 KB

## Abstract It has been demonstrated that the chemopreventive agent __N__‐(4‐hydroxyphenyl)retinamide (4‐HPR) induces apoptotic cell death, but recent data has suggested that late stage/recurrent tumours lose their response to 4‐HPR‐induced cell death by mechanisms that are unknown. Our study inves