## Abstract Adefovir dipivoxil has been used alone or together with lamivudine to suppress lamivudine‐resistant hepatitis B virus (HBV). However, the dynamics of HBV populations under different selection pressures and their impact on treatment outcome are poorly understood. Pyrosequencing® was appl
Combination adefovir–lamivudine prevents emergence of adefovir resistance in lamivudine-resistant hepatitis B
✍ Scribed by David Van Der Poorten; Emilia Prakoso; Teh-Liane Khoo; Meng C Ngu; Geoffrey W McCaughan; Simone I Strasser; Alice U Lee
- Book ID
- 108951540
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 107 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0815-9319
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## Abstract There is little clinical information on the management of hepatitis B virus (HBV) that is resistant to multiple drugs including entecavir (ETV). The present retrospective cohort study assessed the antiviral efficacy of ETV/adefovir dipivoxil (ADV) combination therapy for ETV‐resistant H
## Abstract Serial monotherapy and add‐on regimes for treatment of chronic hepatitis B virus (HBV) infection may induce the accumulation of viral resistance mutations in patients, reducing the options for ongoing viral suppression. The induction of antiviral resistance by serial application of poly