Colorectal Mucinous Adenocarcinoma: The Clinicopathologic Features and Significance of p16 and p53 Expression
β Scribed by Alfred King-Yin Lam; Kate Ong; Yik-Hong Ho
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 366 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0012-3706
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The products of bcl-2 and p53 genes are involved in the regulation of apoptosis and proliferation and have been associated with prognosis in several malignancies, including colorectal adenocarcinoma. Although 2 European studies have reported a prognostic significance of Bcl-2 expression in colorecta
The overexpression of the tumor suppressor gene p53 was investigated immunohistochemically in 144 cases of primary colorectal cancer and in 8 cases with cancer in the corresponding metastatic lymph nodes. Abnormalities in p53 expression were found in 36 cases (25%) of the 144 primary cancer cases. I