## Abstract Deprotonated dipeptides, on collisional activation, fragment by the characteristic process NH~2~CH(R^1^) CONHCH(R^2^)CO~2~^β^ β NH~2~^β^C(R^1^)CONHCH(R^2^)CO~2~H β ^β^NHCH(R^2^)CO~2~H + NH~2~C(R^1^)ο£ΎCο£ΎO, when R^1^ and R^2^ = H or alkyl. However, when one of the constituent amino acids i
Collision induced dissociations of deprotonated peptides: dipeptides containing serine or threonine
β Scribed by Russell J. Waugh; Mark Eckersley; John H. Bowie; Roger N. Hayes
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 485 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0168-1176
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The characteristic coUisionLinduced dissociations of (M -HI-ions of dipeptides and tripeptides involve proton transfer to the carboxylate centre as a prelude to fragmentation. Dipeptides show the process + NH,C(R')=C=O (R = H or alkyl) while tripeptides show the analogous processes NH,CH(R')CONHCH(R
## Abstract The widespread occurrence of the neutral loss of one to six amino acid residues as neutral fragments from doubly protonated tryptic peptides is documented for 23 peptides with individual sequences. Neutral loss of amino acids from the Nβterminus of doubly charged tryptic peptides result